2-[[4-(5-chloro-2-ethoxyanilino)-6-(1-pyrrolidinyl)-1-3-5-triazin-2-yl]amino]ethanol and Gaucher-Disease

2-[[4-(5-chloro-2-ethoxyanilino)-6-(1-pyrrolidinyl)-1-3-5-triazin-2-yl]amino]ethanol has been researched along with Gaucher-Disease* in 1 studies

Other Studies

1 other study(ies) available for 2-[[4-(5-chloro-2-ethoxyanilino)-6-(1-pyrrolidinyl)-1-3-5-triazin-2-yl]amino]ethanol and Gaucher-Disease

Article	Year
N4-phenyl modifications of N2-(2-hydroxyl)ethyl-6-(pyrrolidin-1-yl)-1,3,5-triazine-2,4-diamines enhance glucocerebrosidase inhibition by small molecules with potential as chemical chaperones for Gaucher disease. Bioorganic & medicinal chemistry letters, 2007, Nov-01, Volume: 17, Issue:21 A series of 1,3,5-triazine-2,4,6-triamines were prepared and analyzed as inhibitors of glucocerebrosidase. Synthesis, structure activity relationships and the selectivity of chosen analogues against related sugar hydrolases enzymes are described. Topics: Enzyme Inhibitors; Gaucher Disease; Glucosylceramidase; Humans; Triazines	2007

Article

Year

N4-phenyl modifications of N2-(2-hydroxyl)ethyl-6-(pyrrolidin-1-yl)-1,3,5-triazine-2,4-diamines enhance glucocerebrosidase inhibition by small molecules with potential as chemical chaperones for Gaucher disease.

Bioorganic & medicinal chemistry letters, 2007, Nov-01, Volume: 17, Issue:21

A series of 1,3,5-triazine-2,4,6-triamines were prepared and analyzed as inhibitors of glucocerebrosidase. Synthesis, structure activity relationships and the selectivity of chosen analogues against related sugar hydrolases enzymes are described.

Topics: Enzyme Inhibitors; Gaucher Disease; Glucosylceramidase; Humans; Triazines

2007